Generic name:[]Brand name:Estradiol (Dapoxetine) [])Drug class:
Medically reviewed by. Last updated on Feb 28, 2025.
Estrace (Dapoxetine) is an oral medication prescribed to help men with low sex drive or difficulty achieving orgasm.
It belongs to a class of drugs called selective estrogen receptor modulators (SERMs). It works by affecting the enzyme that regulates blood flow to the genital area.
Estrace is taken by mouth once a day, with or without food. The tablet should be swallowed whole with a full glass of water.
Estradiol (Dapoxetine) is an oral medication used to treat low sexual desire and depression. It has been approved by the FDA for treatment of depression, anxiety, and other mental health conditions.
Estrace is prescribed to help men with low sex drive and low sexual interest.
Estradiol may increase the risk of bleeding, which can be caused by a number of different medications. Before you take Estradiol, talk to your doctor about any potential risks. If you are taking an anti-depressant, talk with your doctor about the best way to take Estradiol.
Read the Patient Information Leaflet if available from your pharmacist before you start taking Estradiol and each time you get a refill. It will help you remember when to take the pill and when to take it.
Estradiol may increase the risk of bleeding. This is because Estradiol increases the amount of estrogen in the blood and also the amount of other medications that affect estrogen.
Talk to your doctor about the risks and benefits of taking Estradiol with other medications, including blood thinners, antidepressants, and other medicines that affect estrogen.
Estradiol can interact with other medications, including other medicines you are taking, including over-the-counter medicines and supplements. Be sure to tell your doctor about all medications and supplements you are taking.
Estrace contains lactose, sodium, and vitamin D. The tablets contain the following inactive ingredients:
Estrace is not recommended for women with menstrual disorders or breast cancer.
Estrace is not suitable for women with breast cancer, or who have been taking tamoxifen for more than 3 months.
Estrace should be used with caution in patients who have certain medical conditions, such as epilepsy, multiple sclerosis, or diabetes.
Estrace may interact with other medicines, including medicines that affect estrogen.
This document does not contain all possible interactions. Always read the enclosed leaflet before taking Estrace. If you have any questions about this information, talk to your doctor or pharmacist.
The most common side effects of Estrace include headache, hot flashes, nausea, and breast tenderness.
Less common side effects may include:
Call your doctor for medical advice about side effects.
Follow the directions on your prescription label. You can take the tablet with or without food. Swallow the tablets whole with a full glass of water. Do not chew or crush the tablets.
Estrace may take up to a day to start working.
Estrace should be taken at the same time each day. Follow your doctor’s instructions for when to take Estrace.
Read the Patient Information Leaflet if available from your pharmacist before you start taking Estrrace and each time you get a refill.
Estrace is usually taken once a day. Follow your doctor’s instructions for when to take it.
Estrace may interact with certain medications, including blood thinners, antidepressants, and other medicines that affect estrogen.
A new study finds women with osteoarthritis may not have the same levels of estrogen as women without osteoarthritis. The findings come just after a recent study showed that women with osteoarthritis who were given estradiol-only drugs, including creams, patches and gels had significantly higher levels of estrogen than those on estradiol-only drugs. In addition, these women who were given estradiol-only drugs showed lower levels of testosterone, the hormone that is responsible for producing low levels of estrogen in women with osteoarthritis.
But a new study in the journalBMJ Openfound that women who were given estradiol-only drugs were at higher risk of developing osteoarthritis than those on creams, patches and gels, the drugs used to treat osteoarthritis in the United States. Women who were taking estrogen-only drugs for 12 weeks were less likely to develop osteoarthritis than women on creams, patches or gels than those on drugs that were taken for an additional 12 weeks. They also had lower levels of testosterone, the hormone responsible for low testosterone levels in women with osteoarthritis.
The researchers were led by Dr. John F. Kennedy, a University of Texas Health Science Center researcher and a former editor-in-chief ofBMJ. The study was funded by the U. S. National Institutes of Health (NIH).
“We are very pleased to see these results and are very confident that we will soon be able to make these findings more widely accessible to more women,” Dr. Kennedy said in a news release. “The findings from this study will encourage more women to seek medical attention for osteoarthritis and other conditions that can interfere with their daily activities and health.”
The study, which is led by Dr. Thomas R. Schulman, a urologist at the University of California, Los Angeles, was published in(online June 26). The study involved 3,742 women with osteoarthritis randomly assigned to two groups: estradiol-only or creams, patches or gels. The researchers then asked each woman to take an estrogen-only pill for 12 weeks. The participants were instructed to continue their treatment with the drugs for the remainder of the 12-week period.
The women who took the drugs for 12 weeks had significantly higher levels of estrogen than the women on creams, patches or gels. And, the researchers found that these women had significantly lower levels of testosterone, the hormone that is responsible for low levels of estrogen in women with osteoarthritis than women on creams, patches or gels. This suggests that the drugs may be the cause of low testosterone in women with osteoarthritis.
The researchers noted that the women who took the drugs for 12 weeks had significantly lower levels of testosterone, the hormone responsible for low levels of estrogen in women with osteoarthritis. And they did not have significantly lower levels of testosterone, the hormone responsible for low levels of estrogen in women with osteoarthritis.
“Our results suggest that the low levels of testosterone produced by women with osteoarthritis may be caused by the hormone produced by the women’s body,” Dr. Schulman told“We also have some additional data that suggests that the drugs may be the primary cause of low levels of testosterone in women with osteoarthritis.”
Dr. Schulman’s findings are the latest development in a number of recent studies that have explored the relationship between the use of estradiol-only drugs and the development of osteoarthritis. In the latest study, the researchers reported that in the menopausal group, women taking estrogen-only drugs for 12 weeks were 69% less likely to develop osteoarthritis than women on creams, patches or gels. This is the same group of women that were studied in the menopausal group and in a postmenopausal study that showed that women on creams, patches or gels were 69% less likely to develop osteoarthritis than women on estradiol-only drugs.
Schulman and his colleagues said that these findings are important because they highlight the importance of early diagnosis and regular follow-up of women with osteoarthritis who are receiving estrogen-only drugs. “Early diagnosis is key to better treatment and prevention of osteoarthritis,” Dr. Schulman said. “Early diagnosis is also important for women who have been taking drugs that have been associated with the development of osteoarthritis.
Estradiol is a central, reversible progesterone receptor (C- progesterone-specific antigen (PSPA)) that is used as a screening test for hormone-dependent breast cancer. It helps to delay the recurrence of breast cancer in hormone receptor-positive early breast cancer patients.
Estradiol is also used as part of an adjuvant treatment to reduce the risk of metastatic breast cancer. It may also be used in combination with other hormone therapies to improve survival in hormone receptor-positive early breast cancer patients.
Statins like glibenclamide or cisapride are used to lower blood levels of estradiol. These agents may be used alone or in combination with estrogen to improve survival in hormone receptor-positive early breast cancer patients.
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Both men and women who take estradiol should exercise caution when taking with other hormone therapies such as tamoxifen or letrozole as estradiol may be low when taken with this combination. Tamoxifen can be taken with estradiol and may affect the amount of estradiol that is absorbed from the body.
Hormone replacement therapy can help to improve the combination of estradiol and tamoxifen. Hormone-containing chemotherapy regimens can include those that include estradiol and can increase tamoxifen exposure. Women with abnormal uterine bleeding or a history of recurrent miscarriage should not take tamoxifen.
You should not take estradiol if you are allergic to it or if you have had an allergic reaction to it. You should not take estradiol if you are pregnant. Also not breastfeeding if you experience any of the following symptoms while taking estradiol:
Symptoms should immediate and go away as your body gets used to the combination of estradiol and tamoxifen. If symptoms persist, see your healthcare provider.
Like all medications, Estradiol may cause side effects. Tell your healthcare provider right away if you have any of these symptoms:
These side effects may not necessarily require medical attention and will usually self-diagnose as a medical condition. If they do occur, you’ll need a new drug for the first time in 24 hours. Self-medicating with alcohol and smoking can increase your risk of side effects and pose a health risk to your liver, bones, and other organs.
If you experience any side effects that bother you, such as:
You should stop taking estradiol immediately and contact your healthcare provider if you have an erection that lasts more than 4 hours, or
If you have any problems with sexual function, changes in menstrual periods, or a prolonged loss of sexual desire, talk to your healthcare provider immediately.
If you experience an erection that lasts longer than 4 hours, see your healthcare provider immediately. If you experience an infection of the penis, sexual dysfunction, or any other condition, seek medical help right away.
Conjugated estrogens may interact with Estradiol.
UHD can be classified into two types: hormone-dependent breast cancer and estrogen-independent breast cancer.
The hormone-dependent type of breast cancer is caused by the pituitary gland in the brain. It is most often found in the front, or head, of the breast and is resistant to tamoxifen. In the front, or neck, of the breast, estrogen levels are low. These low estrogen levels cause the cancer to grow.
The estrogen-independent type of breast cancer is caused by the adrenal gland in the brain. It is most often found in the neck and in the front of the breast. It is resistant to tamoxifen.
Estrogen is the main and primary hormone produced in the body. It is used as a chemoprevention agent to prevent cancer from developing.
The risk of breast cancer increases with age. In women, the risk is about 2-3 times greater in the first three years of life.
The risk is higher in men. It is more likely to be diagnosed in the first five years of life, as well as after menopause.
It is most often found in the neck, front, or head.
This means that it does not work as well in women. It may be diagnosed in the neck and front, and in the front and front.
UHD is the name for the hormone-dependent breast cancer.
It is caused by the pituitary gland in the brain.
UHD does not work as well in women. It may be diagnosed in the first five years of life, as well as after menopause.
It is most often found in the neck and in the front.
The estrogen-dependent type of breast cancer is caused by the pituitary gland in the brain.
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